All eyes will be on Neymar as he and Brazil will look to tamp their authority on Group E which also features Costa Rica, Serbia and Switzerland.
Switzerland are the favorites for the second qualifying spots but they will need to respond well after a testing first match up against Brazil while any hope of Costa Rica and Serbia going through will depend on them getting a result when they meet each other.
Xerdan Shaqiri will be tasked with leading the Switzerland attack while Costa Rica will be hoping that Keylor Navas plays a pivotal role between the sticks.
Serbia has a very solid defense with the likes of Branislav Ivanovic and Aleksandar Kolarov in their ranks while Manchester Uniteds Nemanja Matic will nail down the midfield.
Brazil have a very favorable fixture list which see’s them meet Switzerland first before coming up against Costa Rica and then Serbia.
This should allow Tite ample time to tweak his squad and find his best starting XI before the play offs which given the abundance of talent in his squad might be a tricky task but not one he will bemoan.
Group E should be relatively straightforward with Brazil coming out on top and Switzerland in second although there have already been some surprise results and if Costa Rica or Serbia kick off their campaigns with a win, they have the chance to try cause an upset or two.